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The model was qualified based on standard goodness-of-fit plots of predictions vs observed concentrations and weighted residuals, distribution of individual parameter estimates compared to s.c
False negatives resulting from CYS binding to fetal bovine serum (FBS) present in the cell culture media can be excluded, since we observed only a negligible shift in MIC (2-fold) for the tested reference strain E
That's where treatments like injectable B12 for humans come into play
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